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NADPH provided by the PPP pathway plays a crucial role in the defense against ischemia-induced oxidative stress in neurons

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This highlights its involvement in not just neurological and infectious diseases, but also systemic metabolic conditions

Endothelial Function The endotheliumthe thin layer of cells lining blood vesselsplays a crucial role in regulating blood pressure

Investigated in target-class studies related to adiposity and metabolic dysfunction biology