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In the second protocol, HUVECs (410 4 cells per well) in complete media were simultaneously seeded with DMSO or BPC-157 (1 g/mL, 5 g/mL, and 10 g/mL) in matrigel-coated plates

Having multiple amylin receptor activators designed by this study can be used as potential candidates for the development of novel anti-obesity peptide drugs

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Assuming Eli Lilly follows a similar timeline to tirzepatide, the earliest possible FDA approval for retatrutide would likely occur in late 2027 or 2028, depending on Phase 3 trial results and regulatory review timelines