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NHS article about B12 deficiency nhs.uk/conditions/vitamin-b

John, G

Additionally, a limitation of the present study is its reliance on available evidence from the preclinical level, which reported associative biochemical markers (e.g., SOD, GSH) to infer mechanistic protection

And that brings us back to the central question

It also modulates pineal gland function and circadian biologyrestoring nighttime melatonin release and normalizing disrupted sleepwake rhythms in older humans and animals