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After 6 hours (which equals 6 half-lives), the maximum and minimum drug concentrations become constant, further drug accumulation does not occur, and the drug is steady-state

Examples of selective and non-selective forms of affinity chromatography with the functional group (ligand) used for specificity and typical elution conditions

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Variola proteins that may be hindered include those involved in viral replication, for example, encoded viral DNA topoisomerases, and those involved in evasion of host immunologic defenses

Abdelrazik H, Sharma R, Mahfouz R, Agarwal A