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Gwathmey, Zhenghang Zhao Pflgers Archiv - European Journal of Physiology.2021

If you see a biological effect hours after a single subcutaneous injection, it's critical to question the mechanism

Subsequently, Western Blot (WB) analysis detected a decrease in total P53 expression but an increase in phosphorylated P53 (p-P53) expression in OGD-induced senescent endothelial cells post FOXO4-DRI treatment (Figures 5B,C)

Biological process (BP) over-representation analysis and Gene Set Enrichment Analysis (GSEA) were performed using Clusterprofiler (version 4.0.5) 58 and org.Ce.eg.db (version 3.13.0)

11 Cardiac arrhythmia has also been reported and is associated with a cytokine storm-triggered systemic hyperinflammatory state and immune response that may cause injury to cardiac monocytes, resulting in myocardial dysfunction and the ensuing development of arrhythmia