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Annual intramuscular injection of a megadose of cholecalciferol for treatment of vitamin D deficiency: Efficacy and safety data

doi: 10.4161/15548627.2014.981787 38 ShihC.-C.HsuY.-T.WangH.-H.ChenT.-L.TsaiC.-C.LaneH.-L.et al

Conclusion The current study enumerates a step-by-step design of experiments for the solubilization of IB proteins (probably of the non-classical type) for two amphipathic helices harboured on an AKAP (FAP65) that were surprisingly insoluble even after fusion with GST, a commonly used solubility-enhancer tag while producing recombinant proteins

We can't jump from personal experiences to assuming that some biological process is not working when we don't yet even have a good idea of how that process would work in a healthy person yet

It increases the expression of VEGF and its receptor VEGFR2, delivering nutrients and oxygen to injured tissues to speed up healing