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This means that at high plasma levels of thiosulfate, secretion Tm (transfer maximum) is similar to reabsorption Tm, whereas at low plasma levels both filtered and secreted thiosulfate are reabsorbed and thus there is a diminished clearance value for thiosulfate

Its value is in what it adds when combined with GLP-1 agonism

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Oral supplementation with beta-hydroxy-beta-methylbutyrate, arginine, and glutamine improves lean body mass in healthy older adults