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Studies using cDC models have shown that ROS produced by DCs during antigen cross-presentation help maintain an alkaline environment within the phagosome, which is crucial for preserving the structure of internalized antigens and successfully presenting them via Major Histocompatibility Complex class I (MHC-I) complexes to CD8 + T cells [157]

To confirm the results for the cancer cell lines, we performed IF to detect PML bodies, a marker of ALT

The cell produces free radicals as a byproduct of the chemical events that take place within it

Mercer SW, Wang J, Burke R (2017) In vivo modeling of the pathogenic effect of copper transporter mutations that cause Menkes and Wilson diseases, motor neuropathy, and susceptibility to Alzheimers disease

Bayatli F, Akku D, Kilic E, Saraymen R, Snmez MF