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This malabsorption can lead to various health problems, including malnutrition, weakened bones, mood changes, and reproductive issues

Many solid tumors and hematological malignancies lack MTAP, and thus inhibitors of purine synthesis and methionine deprivation may be potential therapeutic strategies for MTAP-deficient tumors [283]

Weight loss drugs can have several common side effects

Starting the injectable on the day after the last orforglipron dose, at the injectable's standard starting dose with normal titration, provides a straightforward transition