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Acknowledgements We gratefully acknowledge the financial support from Eurostars (project Nr

Nordihydroguaiaretic acid suppresses ferroptosis and mitigates intervertebral disc degeneration through the nrf2/gpx4 axis

Structurally, IgV domains are slightly larger than IgC domains, having more strand elaborations on the basic Ig domain fold (Halaby et al., 1999)

Interestingly, despite the presence of superoxide dismutase (SOD) ( k = 2.4 10 9 M 1 s 1 ) 36 , the resulting concentration of H 2 O 2 is significantly smaller than the concentration of superoxide, indicating that the model is able to respond well to a transient increase in ROS, maintaining low H 2 O 2 concentrations