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R 6 is H or halogen R 7 is H, methyl, or NR 11 R 12

For example, in a new study, patients who first used a daily topical treatment gel containing 0.1% adapalene and 2.5% benzoyl peroxide for 2-4 weeks before undergoing 3 treatments with Sebacia, spaced 1-2 weeks apart, saw an improvement of 66% at 3 months, as compared to those who had Sebacia alone (in the clinical trials), and showed 49% improvement at 3 months

See the Reconstitution Guide for handling details

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Regular monitoring for signs and symptoms of thrombosis is recommended while taking this medication