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Pharmacogenomics J (2017) 17:1629

2 other patients acquired severe electrolyte abnormalities

10.1016/j.fertnstert.2007.08.039 84 MalikM.MendozaM.PaysonM.CatherinoW

Figure 2 Excessive intracellular Ca 2+ levels trigger the opening of the mitochondrial permeability transition pore (MPTP), resulting in the loss of mitochondrial membrane potential and hindering ATP production (50)