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Polyphenol exposure and risk of type 2 diabetes: dose-response meta-analyses and systematic review of prospective cohort studies

69 BhalchandraWAlqadhiYA

10.1016/j.jss.2011.06.033 J Surg Res

In ischemia-reperfusion injury, chemokines and cytokines recruit immune cells to the injury site and activate them to produce a cascade of inflammatory mediators

Notably, EPAS1 (which encodes HIF-2) has shown a strong selection signal and is correlated with lower hemoglobin concentrations in Tibetans [2,3,4,5], whereas HIF1A (which encodes HIF-1) has not shown clear signs of selection among Tibetans [3]