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doi: 10.3390/ph16101471 157

Strong Reduction of the Chain Rigidity of Hyaluronan by Selective Binding of Ca2+ Ions

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The overall risks for each of the two primary endpoints (the cardiovascular composite and the renal composite) were not reduced with darbepoetin alfa treatment (see Table 1), but the risk of stroke was increased nearly two-fold in the darbepoetin alfa -treated group versus the placebo group: annualized stroke rate 2.1% vs