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The possible toxic effects exerted by oxygen-derived species are counteracted with antioxidant systems, so that a proper intracellular environment is maintained

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The authors hypothesized that male mice may develop a tolerance to acetone because hepatic changes were not observed in male mice in the second study, the 13-week NTP study presented in the next section

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32 StahlNBoultonTGFarruggellaTIpNYDavisSWitthuhnBAet alAssociation and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components