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c-Myc has been demonstrated to play a crucial role in promoting the expression of genes associated with glycolysis, including Glut1, Glut2, Glut3, Glut4, hexokinase, phosphoglucose isomerase, phosphofructokinase, aldolase A, triose phosphate isomerase, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase 1, phosphoglycerate mutase, enolase, pyruvate kinase, and LDHA [141] (Fig