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Fucoidan protects mesenchymal stem cells against oxidative stress and enhances vascular regeneration in a murine hindlimb ischemia model

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The Journal of the American Society of Hematology 2022;139:245059

Adequate maternal folate status protects against neural tube defects and supports proper brain development, while deficiency is associated with persistent alterations in offspring neurodevelopment and an increased risk of obesity and insulin resistance later in life [112,113,114]

Upstream regulatory pathways and transcription factors p53 pathway p53 is a master stress-responsive transcription factor that governs cell-cycle arrest, senescence and apoptosis, and its functional inactivation represents a central event in tumorigenesis