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Another challenge to overcome for the next-generation nanomedicines resides in the regulatory classification, because the lack of knowledge regarding biosafety and long-term effects of nanomaterials leads to a regulatory uncertainty and deficient standards and protocols for scale-up manufacturing and safe clinical uses [678,679]

39,95 Prices may be subject to local taxes which are calculated during checkout Similar content being viewed by others Change history 21 March 2023 A Correction to this paper has been published: References Scherlinger, M

doi: 10.1016/j.mib.2017.07.003

Mice with apolipoprotein E deficiency and knocked down NF-B p50 showed higher serum levels of TNF-, IL-6, and cholesterol and more pronounced atherosclerotic lesions than mice with apolipoprotein E deficiency alone ( Upstream of NF-B has also been discussed in the IH-mediated AS