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& Princen, H.M

Panov J, Simchi L, Feuermann Y, Kaphzan H

doi:10.1016/j.jand.2020.07.014 28

In stable patients, diaphragmatic injury and adaptation achieved a special balance ( In the future, diaphragm dysfunction in patients with mild to moderate COPD should be the focus of research

However, PINK1 overexpression did not enhance CSE-induced mitophagy or restore the mitophagy impairment caused by PRKN knockdown, suggesting that PRKN protein levels may be the primary rate-limiting factor in PINK1/PRKN-mediated mitophagy ( Although the PINK1/Parkin pathway is generally regarded as the dominant mechanism regulating mitophagy, mitophagy can still be maintained in the absence of PINK1 or Parkin