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Medzhitov R (2008) Origin and physiological roles of inflammation

(b) Fluorescence intensity of Aaf group cells

The cardioprotective effects observed in vitro were confirmed in the study by Wang and colleagues, who demonstrated that daily administration of the sodium salt NaHS (80 M/day, intraperitoneally, for up to 12 weeks) significantly prevented the impairment in left ventricular systolic and diastolic functions, mitochondrial alterations (i.e., enlargement of organelles), and cardiomyocytes apoptosis in rats with HHcy induced by L-Met (2 g/kg/day, dissolved in 2.5% starch, by gavage, for 18 weeks) [131]

However, in contrast to the tumour-suppressive effects described above, there is evidence that CDO1 can have a tumorigenic effect associated with aggressive glioblastoma, since its overexpression was detected in these tumours

Neurosci Lett 471:134138 Dufy L, Roach P, Naumovski N (2015) Green tea catchins as neuroprotective agents: systematic review of the literature in animal pre-clinical trials