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While multi-omics studies link microbial signatures, BA profiles, and cancer outcomes (Section 4.3), their precise mechanistic underpinnings are often elusive, a recognized issue in complex diseases (163, 187, 188)

When the tumor reached 100150 mm 2 , mice were divided into three groups following the principle of randomness and respectively received subcutaneous Intraperitoneal injection every two days with Tween80 (vehicle control, 100 l), GSPT1 inhibitor (HY135318