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Single molecule glycosylase studies with engineered 8-oxoguanine DNA damage sites show functional defects of a MUTYH polyposis variant

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Therefore, we next examined a loss of function allele of gst-4 generated by CRISPR/Cas9

Ciccia F, Haroon N

It is interesting, however, that evaluation of small fiber function as performed by QST (that is, thermal thresholds) did not show significant changes following ARA 290 administration