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10.1016/j.artmed.2023.102690 13

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Our findings suggest that some lymphoid cells accumulate in G 0 /G 1 or G 2 /M, while others experience minimal alteration in cell cycle distribution

6.1 Glutathione metabolism: modern view of biosynthetic pathways, NADPH dependence, and relationship to thioredoxin The synthesis of glutathione (GSH) predominantly occurs through the ATP-dependent -glutamyl cycle, beginning with the action of glutamate-cysteine ligase (GCL), the key rate-limiting enzyme composed of two subunits: a catalytic component (GCLC) and a regulatory modifier (GCLM)