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For instance, under hypoxic conditions, lactylation of the transcription factor Yin Yang 1 at its K183 site by p300 directly activates the fibroblast growth factor 2 signaling pathway, leading to tumor angiogenesis (86)

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For example, IV GSH infusions were shown to significantly prevent nerve damage (neuropathy) associated with the chemotherapy drug cisplatin in patients with advanced gastric cancer Topical and Combination Efficacy: Studies confirm that topical application (for example, a 2 percent lotion) can reduce melanin indices and improve skin texture, particularly in conditions like melasma

2012) and optimization of targeting signal peptides (Karyolaimos et al