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By using advanced laboratory methods, the researchers examined how THI reacts with these biomolecules under conditions similar to those in the human body

While it is generally understood that efflux pumps often play an important role in drug-resistant phenotypes, it remains poorly defined how molecular structure drives recognition by efflux pumps

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In an autologous blood injection model of ICH, PDZ improves neurological recovery, an effect blocked by the Nrf2 inhibitor ML385, demonstrating that PPAR/Nrf2/GPX4 signaling underlies its protective mechanism (197)

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