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For example, mutations that hide the degron in oncoproteins result in a buildup of these proteins, which help them drive cancer formation and progression (Micel et al, 2013

antibodies are generated that include the heavy and/or light chain CDR3s of the particular antibodies described herein (e.g., M25ADLF, M25ADLFEG, M25ADLFDS, M25FYIA, M25FYIAEG, M25FYIADS, M25, M25EG, M25DS, antibodies are generated that include the heavy and/or light chain CDRls of the particular antibodies described herein (e.g., M25ADLF, M25ADLF, M25ADX, ALPPL2rd3_l, ALPPL2rd3_2, M25AGIA, M25AGLF, M25ASIA, M25ASLF, M25ASwt, M25AVIA, M25AVLF, M25ALIA, M25ALLF, M25wtIA, and/or M25wtLF)

This axis responds to physical or psychological stressors, releasing corticotrophin-releasing hormone (CRH) from the hypothalamus

These enzymes include: superoxide dismutase glutathione peroxidise glutathione reductase catalases These form the bodys endogenous defence mechanisms to help protect against free radical-induced cell damage

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