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The resulting structures show a slight shift of the N-terminal -helix upon phosphorylation, most probably due to electrostatic repulsion between the phosphate and E325, E375, and D424

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doi: 10.1007/s10147-019-01404-2 Summary Keywords lynch syndrome, fertility-sparing treatment, atypical endometrial hyperplasia, endometrial cancer, oncology outcome Citation Hsu Y-T and Chen C-H (2024) Progression of fertility-sparing treatment for atypical endometrial hyperplasia in a woman with lynch syndrome: a case report and review of the literature

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To study the effect of each of those parameters on zonation and define the alteration of the parameters, we introduced controlled levels of zonation for each of the zonated metabolic parameters