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As with vaping, this mimics the hand-to-mouth action of smoking, which can be useful for replacing the physical element of the habit

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The most important regulatory factor is CC chemokine receptor 2 (CCR2) and its ligands monocyte chemoattractant protein 1 (MCP-1) and monocyte chemoattractant protein 3 (MCP-3) (8183)

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